Cumulative Clicker Practice Test 2025 - Free Practice Questions and Study Guide

The interaction between GTP and a G-protein at an active site is crucial for initiating cellular signaling pathways. When GTP binds to the G-protein, it triggers a conformational change that activates the G-protein, allowing it to interact with other downstream effectors in the signaling pathway. This activation is essential for the subsequent hydrolysis of GTP to GDP, which ultimately leads to the initiation of signal transduction.

When GTP is bound, the G-protein is in its active form, capable of transmitting signals that can result in a variety of cellular responses. This process is fundamental in many physiological responses and is a key mechanism in how cells respond to external stimuli. Therefore, the expected outcome of the interaction between GTP and the G-protein is indeed to initiate GTP hydrolysis and subsequent signaling, aligning precisely with the function of G-proteins in cellular communication.